Once the cheats are selected, use CDVD > ISO Selector to switch to your game ISO. Resume the game, and the cheats will be applied. How to Safely Find and Download CodeBreaker v10.1
Once you've downloaded the Codebreaker V10.1 PS2 ISO, it's time to use it. Here's a step-by-step guide: download codebreaker v10.1 ps2 iso